D17

LUNG - "Malignant histiocytosis"

Description of Specimen
The pleural surface of the lung shows an extensive exudate with a number of slightly raised pale areas. The cut surface shows a central, rather poorly-defined tumour mass with small nodules of tumour scattered throughout the lung. The histology of the lesion was that of "malignant histiocytosis"; the exact position of this disorder in the spectrum of lympho-reticular disease is not clear.
History
At the age of 10, this child presented with a short history of fever, abdominal and chest pain, lethargy, shortness of breath, loss of appetite, nausea and vomiting. Examination showed numerous enlarged lymph nodes and an enlarged liver and spleen. Radiologically there was evidence of infiltration in the lungs. The child died fifteen days after admission.